Endocrine Abstracts

Kisspeptin is a crucial activator of reproductive function, stimulating GnRH neurons in the hypothalamus. However, kisspeptin and its receptor are also expressed in other brain regions including the limbic system, which has key roles in emotional processing. Kisspeptin signalling in the limbic system modulates emotional and sexual brain processing during tasks, however the effects of kisspeptin on underlying resting brain activity have not yet been studied. This is vital for o...

Kisspeptin is a crucial activator of reproductive function, stimulating GnRH neurons in the hypothalamus. However, kisspeptin and its receptor are also expressed in other brain regions including the limbic system, which has key roles in emotional processing. Kisspeptin signalling in the limbic system modulates emotional and sexual brain processing during tasks, however the effects of kisspeptin on underlying resting brain activity have not yet been studied. This is vital for o...

Kisspeptin is a crucial activator of reproductive function, playing a critical role in the hypothalamus to activate GnRH neurons and downstream reproductive hormones. However, kisspeptin and its receptor are also expressed in other brain areas, yet little is known about their function here. The limbic system plays a key role in sexual and emotional behaviours and has a high expression of kisspeptin receptors. We therefore hypothesised that kisspeptin administration may modulat...